Routines for the functional analysis of biological networks //
This package provides functions for the integrated analysis of
protein-protein interaction networks and the detection of
functional modules. Different datasets can be integrated into
the network by assigning p-values of statistical tests to the
nodes of the network. E.g. p-values obtained from the
differential expression of the genes from an Affymetrix array
are assigned to the nodes of the network. By fitting a beta-
uniform mixture model and calculating scores from the p-values,
overall scores of network regions can be calculated and an
integer linear programming algorithm identifies the maximum
scoring subnetwork.